PDB ID: 4RUP
Hetero Atom Contents
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H97 | (1r,3r,7e,17beta)-17-[(1r)-6,6,6-trifluoro-5-hydroxy-1-(4-hydroxy-4-methylpentyl)-5-(trifluoromethyl)hex-3-yn-1-yl]-9,1 0-secoestra-5,7-diene-1,3-diol | PoSSuM |
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Download interaction data: 4RUP
Structure summary
Code : | 4RUP PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | Transcription Factor | ||||||||||||||||||||||||
Title : | Crystal structure of zVDR L337H mutant-Gemini72 complex | ||||||||||||||||||||||||
Release Data : | 2015-10-07 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Huet, T., Moras, D., Rochel, N. | ||||||||||||||||||||||||
Keywords : | alpha helical sandwich, transcription factor, retinoid X receptor, ligand, DNA, phosphorylation, nucleus | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.750 Å ) | ||||||||||||||||||||||||
Citation : |
A vitamin D receptor selectively activated by gemini analogs reveals ligand dependent and independent effects.
Huet, T.,Laverny, G.,Ciesielski, F.
et al.
PubMed: 25620699 |
Reaction
Chain : | A |
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UniProt : | Q9PTN2 (VDRA_DANRE) |
Reaction : | - |
Chain : | B | ||||||||
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UniProt : | Q15788 (NCOA1_HUMAN) | ||||||||
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