PDB ID: 4PVY
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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GOL | Glycerol | PoSSuM | |||
JD1 | [({5-[4-(propan-2-yloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid) | PoSSuM | |||
MG | Magnesium ion | PoSSuM |
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Download interaction data: 4PVY
Structure summary
Code : | 4PVY PDBj RCSB PDB PDBe | ||||||||||||
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Header : | Transferase/transferase inhibitor | ||||||||||||
Title : | Crystal structure of human FPPS in complex with [({5-[4-(propan-2-yloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid) | ||||||||||||
Release Data : | 2015-04-15 | ||||||||||||
Compound : |
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Source : |
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Authors : | Rodionov, D., Park, J., De Schutter, J.W., Tsantrizos, Y.S., Berghuis, A.M. | ||||||||||||
Keywords : | Transferase-transferase inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.05 Å ) | ||||||||||||
Citation : |
Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
Park, J.,Rodionov, D.,De Schutter, J.W.
et al.
PubMed: 29036218 |
Reaction
Chain : | F | ||||||||||||
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UniProt : | P14324 (FPPS_HUMAN) | ||||||||||||
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