Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
MN Manganese (II) ion
FOL Folic acid
NAP Nadp nicotinamide-adenine-dinucleotide phosphate
Modified Residues
Code Name Link
CSD 3-sulfinoalanine
Code : 4PTH
Header : OXIDOREDUCTASE
Title : Ensemble model for Escherichia coli dihydrofolate reductase at 100K
Release Data : 2014-05-14
Compound :
mol_id molecule chains
1 Dihydrofolate reductase A
ec: 1.5.1.3
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:316385) Escherichia coli  (taxid:469008)
strain: K12 / DH10B
gene: folA, ECDH10B_0049
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: pET22b
Authors : Keedy, D.A., van den Bedem, H., Sivak, D.A., Petsko, G.A., Ringe, D., Wilson, M.A., Fraser, J.S.
Keywords : ROSSMANN FOLD, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 0.85 Å )
Citation :

Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR.

Keedy, D.A.,van den Bedem, H.,Sivak, D.A.  et al.
(2014)  Structure  22 : 899 - 910

PubMed: 24882744
DOI: 10.1016/j.str.2014.04.016

Chain : A
UniProt : B1XC49 (No found in current UniProtKB/SwissProt)
Reaction : -