Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
C Cytidine-5'-monophosphate
MG Magnesium ion
Code : 4M2Z
Header : HYDROLASE/RNA
Title : Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE)
Release Data : 2013-12-11
Compound :
mol_id molecule chains synonym
1 Ribonuclease 3 A,B Ribonuclease III, RNase III
ec: 3.1.26.3
mol_id molecule chains
2 RNA10 C,D
Source :
mol_id organism_scientific expression_system
1 Aquifex aeolicus  (taxid:224324) Escherichia coli  (taxid:469008)
strain: VF5
gene: aq_946, rnc
expression_system_strain: BL21(DE3) CodonPlus-RIL
expression_system_vector_type: PLASMID
expression_system_plasmid: pHPK1409
mol_id organism_scientific
2
synthetic: yes
other_details: Cleavage product of a R1.1 RNA derivative
Authors : Gan, J., Liang, Y.-H., Shaw, G.X., Tropea, J.E., Waugh, D.S., Ji, X.
Keywords : RNase III, Hydrolase, dsRNA, RNA binding, RNA processing, HYDROLASE-RNA complex
Exp. method : X-RAY DIFFRACTION ( 2.8500 Å )
Citation :

RNase III: Genetics and Function; Structure and Mechanism.

Court, D.L.,Gan, J.,Liang, Y.H.  et al.
(2013)  Annu. Rev. Genet.  47 : 405 - 431

PubMed: 24274754
DOI: 10.1146/annurev-genet-110711-155618

Chain : A, B
UniProt : O67082 (RNC_AQUAE)
Reaction : Endonucleolytic cleavage to 5'- phosphomonoester.