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Ligands
Code Name Style Show Link
FOL Folic acid
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
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Code : 4LRH   PDBj   RCSB PDB   PDBe
Header : Folate Binding Protein
Title : Crystal structure of human folate receptor alpha in complex with folic acid
Release Data : 2013-07-31
Compound :
mol_id molecule chains synonym
1 Folate receptor alpha A,B,C,D,E,F,G,H FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, adult, KB cells FBP, Ovarian tumor-associated antigen MOv18
fragment: Folate receptor alpha
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Homo sapiens  (taxid:9606)
gene: FOLR1, FOLR
expression_system_cell_line: mammalian cell line
Authors : Ke, J., Chen, C., Zhou, X.E., Yi, W., Brunzelle, J.S., Li, J., Young, E.-L., Xu, H.E., Melcher, K.
Keywords : folate receptor-alpha, folic acid, folate binding protein, cysteine-rich glycoprotein
Exp. method : X-RAY DIFFRACTION ( 2.8000 Å )
Citation :

Structural basis for molecular recognition of folic acid by folate receptors.

Chen, C.,Ke, J.,Zhou, X.E.  et al.
(2013)  Nature  500 : 486 - 489

PubMed: 23851396
DOI: 10.1038/nature12327

Chain : A, B, C, D, E, F, G, H
UniProt : P15328 (FOLR1_HUMAN)
Reaction : -