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Ligands
Code Name Style Show Link
RL3 [5-(6-bromo[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dihydroxyphenyl](4-methylpiperazin-1-yl)methanone
Non-standard Residues
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Code : 4L90   PDBj   RCSB PDB   PDBe
Header : Chaperone/Chaperone Inhibitor
Title : Crystal structure of Human Hsp90 with RL3
Release Data : 2014-06-18
Compound :
mol_id molecule chains synonym
1 Heat shock protein HSP 90-alpha A Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38
fragment: UNP residues 9-236
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: HSP90AA1
Authors : Li, J., Ren, J., Yang, M., Xiong, B., He, J.
Keywords : ATP hydrolysis, Hsp90N-Hsp90N Inhibitor complex, Chaperone-Chaperone Inhibitor complex
Exp. method : X-RAY DIFFRACTION ( 2.001 Å )
Citation :

Crystal structure of Human Hsp90 with RL3

Li, J.,Ren, J.,Yang, M.  et al.
to be published 

Chain : A
UniProt : P07900 (HS90A_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
ATP + H2O = ADP + H(+) + phosphate 3.6.4.10 PubMed:12526792
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