PDB ID: 4L3O
Hetero Atom Contents
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Structure summary
Code : | 4L3O PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||||||||||||||
Title : | Crystal Structure of SIRT2 in complex with the macrocyclic peptide S2iL5 | ||||||||||||||||||||||||
Release Data : | 2014-02-19 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Yamagata, K., Nishimasu, H., Ishitani, R., Nureki, O. | ||||||||||||||||||||||||
Keywords : | macrocyclic peptide, structural change, HYDROLASE-HYDROLASE INHIBITOR complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.5180 Å ) | ||||||||||||||||||||||||
Citation : |
Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change
Yamagata, K.,Goto, Y.,Nishimasu, H.
et al.
PubMed: 24389023 |
Reaction
Chain : | A, B, C, D | ||||||||||||||||
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UniProt : | Q8IXJ6 (SIR2_HUMAN) | ||||||||||||||||
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