Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
DT Thymidine-5'-monophosphate
MG Magnesium ion
BME Beta-mercaptoethanol
EDO 1,2-ethanediol
EPE 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
Code : 4KX3
Header : HYDROLASE
Title : Structure of murine cytosolic 5'-nucleotidase III complexed with thymidine monophosphate
Release Data : 2013-06-05
Compound :
mol_id molecule chains synonym
1 Cytosolic 5'-nucleotidase 3 A Cytosolic 5'-nucleotidase III, cN-III, Lupin, Pyrimidine 5'-nucleotidase 1, P5'N-1, P5N-1, PN-I
ec: 3.1.3.5
fragment: Catalytically Inactive cN-III
mutation: D51N, M1S
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) Mouse Escherichia coli  (taxid:562)
gene: Nt5c3
expression_system_strain: Rosetta 2
expression_system_vector_type: PLASMID
expression_system_plasmid: pVP16-GW
Authors : Bitto, E., Bingman, C.A., Grobosky, C.L.
Keywords : SUBSTRATE COMPLEX, HAD SUPERFAMILY, NUCLEOTIDASE, UMPH-1, CYTOSOLIC 5'-NUCLEOTIDASE III, P5N-1, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.1000 Å )
Citation :

Structure of murine cytosolic 5'-nucleotidase III complexed with thymidine monophosphate

Bitto, E.,Bingman, C.A.,Grobosky, C.L.
To be Published 

Chain : A
UniProt : Q9D020 (5NT3A_MOUSE)
Reaction : N(7)-methyl-GMP + H(2)O = N(7)-methyl- guanosine + phosphate.
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.