Brand  (β version)

PDB ID: 4KX3

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Ligands
Code Name Style Show Link
BME Beta-mercaptoethanol PoSSuM
DT Thymidine-5'-monophosphate PoSSuM
EDO 1,2-ethanediol PoSSuM
EPE 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid PoSSuM
MG Magnesium ion PoSSuM
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Structure summary

Code : 4KX3   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Structure of murine cytosolic 5'-nucleotidase III complexed with thymidine monophosphate
Release Data : 2013-06-05
Compound :
mol_id molecule chains synonym
1 Cytosolic 5'-nucleotidase 3 A Cytosolic 5'-nucleotidase III, cN-III, Lupin, Pyrimidine 5'-nucleotidase 1, P5'N-1, P5N-1, PN-I
ec: 3.1.3.5
fragment: Catalytically Inactive cN-III
mutation: D51N, M1S
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) Mouse Escherichia coli  (taxid:562)
gene: Nt5c3
expression_system_strain: Rosetta 2
expression_system_vector_type: PLASMID
expression_system_plasmid: pVP16-GW
Authors : Bitto, E., Bingman, C.A., Grobosky, C.L.
Keywords : SUBSTRATE COMPLEX, HAD SUPERFAMILY, NUCLEOTIDASE, UMPH-1, CYTOSOLIC 5'-NUCLEOTIDASE III, P5N-1, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.1000 Å )
Citation :

Structure of murine cytosolic 5'-nucleotidase III complexed with thymidine monophosphate

Bitto, E.,Bingman, C.A.,Grobosky, C.L.
To be Published 

Reaction

Chain : A
UniProt : Q9D020 (5NT3A_MOUSE)
Reaction: EC: Evidence:
Physiological Direction:
H2O + N(7)-methyl-GMP = N(7)-methylguanosine + phosphate 3.1.3.91 UniProtKB:Q9H0P0
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a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate 3.1.3.5 PubMed:16672222
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