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Ligands
Code Name Style Show Link
ACT Acetate ion
FMN Flavin mononucleotide
JTS 4-methyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide
ORO Orotic acid
SO4 Sulfate ion
Non-standard Residues
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Code : 4JTS   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 072
Release Data : 2014-03-26
Compound :
mol_id molecule chains synonym
1 Dihydroorotate dehydrogenase (quinone), mitochondrial A DHOdehase, Dihydroorotate oxidase
ec: 1.3.5.2
fragment: UNP residues 29-395
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: DHODH
Authors : Zhu, L., Zhu, J., Ren, X., Li, H.
Keywords : DHODH, oxidoreductase, FMN binding, mitochondria inner membrane
Exp. method : X-RAY DIFFRACTION ( 2.206 Å )
Citation :

Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057

Zhu, L.,Li, H.,Zhu, J.  et al.
To be Published 

Chain : A
UniProt : Q02127 (PYRD_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
(S)-dihydroorotate + a quinone = a quinol + orotate 1.3.5.2 PubMed:8925840
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