PDB ID: 4IU6
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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CO | Cobalt (II) ion | PoSSuM | |||
FZ1 | 4-[4-(4-methoxyphenyl)piperazin-1-yl]-2-(pyridin-2-yl)quinazoline | PoSSuM | |||
K | Potassium ion | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
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Download interaction data: 4IU6
Structure summary
Code : | 4IU6 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | hydrolase/hydrolase inhibitor | ||||||||||||
Title : | Human Methionine Aminopeptidase in complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1 | ||||||||||||
Release Data : | 2013-05-01 | ||||||||||||
Compound : |
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Source : |
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Authors : | Gabelli, S.B., Zhang, F., Miller, M., Liu, J., Amzel, L.M. | ||||||||||||
Keywords : | MetAp1, Methionine Aminopeptidase 1, Methionine Aminopeptidase, hydrolase-hydrolase inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.9000 Å ) | ||||||||||||
Citation : |
Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells.
Zhang, F.,Bhat, S.,Gabelli, S.B.
et al.
PubMed: 23634668 |
Reaction
Chain : | A | ||||||||
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UniProt : | P53582 (MAP11_HUMAN) | ||||||||
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