Het-PDB Navi2 (PDB: 4HJX)

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Ligands
Code	Name		Style	Show	Link
F2Y	3,5-difluoro-L-tyrosine				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 4HJX

Code :

4HJX PDBj RCSB PDB PDBe

Header :

LIGASE

Title :

Crystal structure of F2YRS complexed with F2Y

Release Data :

2013-03-13

Compound :

mol_id	molecule	chains	synonym
1	Tyrosine-tRNA ligase	A,B	Tyrosyl-tRNA synthetase, TyrRS
	mutation: Y32R,L65Y,H70G,F108N,Q109C,D158N,L162S

Source :

mol_id	organism_scientific	expression_system
1	Methanococcus Jannaschii DSM 2661 (taxid:243232)	Escherichia coli (taxid:562)
	strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440 gene: tyrS, MJ0389

Authors :

Wang, J., Tian, C., Gong, W., Li, F., Shi, P., Li, J., Ding, W.

Keywords :

AMINOACYL-TRNA SYNTHETASE, LIGASE

Exp. method :

X-RAY DIFFRACTION ( 2.910 Å )

Citation :

A genetically encoded 19F NMR probe for tyrosine phosphorylation.

Li, F.,Shi, P.,Li, J. et al.
(2013) Angew.Chem.Int.Ed.Engl. 52 : 3958 - 3962

Chain :

A, B

UniProt :

Q57834 (SYY_METJA)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)	6.1.1.1	-
	-	-

PDB ID: 4HJX