Brand  (β version)

PDB ID: 4H7U

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Ligands
Code Name Style Show Link
FED [(2r,3s,4r,5r)-5-(6-amino-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2r,3s,4s)-2,3,4-trihydroxy-5-[(4ar)-4a-hydroxy-7,8-dimethyl-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[G]pteridin-10(2h)-yl]pentyl dihydrogen diphosphate (non-preferred name) PoSSuM
PO4 Phosphate ion PoSSuM
Non-standard Residues
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Glycosylation
Code Name Emphasize
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
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Structure summary

Code : 4H7U   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of pyranose dehydrogenase from Agaricus meleagris, wildtype
Release Data : 2013-08-07
Compound :
mol_id molecule chains
1 Pyranose dehydrogenase A
ec: 1.1.99.29
Source :
mol_id organism_scientific expression_system
1 Leucoagaricus meleagris  (taxid:201219) Komagataella pastoris  (taxid:4922)
gene: pdh1
expression_system_strain: CBS 7435
expression_system_vector_type: Plasmid
Authors : Tan, T.C., Spadiut, O., Divne, C.
Keywords : pyranose dehydrogenase, flavin adduct, GMC-oxidoreductase family, glycoprotein, Rossmann fold/FAD-linked reductases/Alpha and beta proteins (a+b), Oxidoreductase, FAD binding, Flavin C(4a) oxygen adduct, Secreted
Exp. method : X-RAY DIFFRACTION ( 1.60 Å )
Citation :

The 1.6 A crystal structure of pyranose dehydrogenase from Agaricus meleagris rationalizes substrate specificity and reveals a flavin intermediate.

Tan, T.C.,Spadiut, O.,Wongnate, T.  et al.
(2013)  Plos One  8 : e53567 - e53567

PubMed: 23326459
DOI: 10.1371/journal.pone.0053567

Reaction

Chain : A
UniProt : Q3L245 (PDH1_LEUMG)
Reaction: EC: Evidence:
Physiological Direction:
pyranose + acceptor = pyranos-2-ulose + reduced acceptor. 1.1.99.29 PubMed:18083263, Ref.3, Ref.4
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pyranose + acceptor = pyranos-3-ulose + reduced acceptor. 1.1.99.29 PubMed:18083263, Ref.3, Ref.4
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pyranose + acceptor = pyranos-2,3-diulose + reduced acceptor. 1.1.99.29 PubMed:18083263, Ref.3, Ref.4
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a pyranoside + acceptor = a pyranosid-3-ulose + reduced acceptor. 1.1.99.29 PubMed:18083263, Ref.3, Ref.4
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a pyranoside + acceptor = a pyranosid-3,4-diulose + reduced acceptor. 1.1.99.29 PubMed:18083263, Ref.3, Ref.4
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