PDB ID: 4GQ3
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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0RO | 4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]-6-propylthieno[2,3-D]pyrimidine | PoSSuM | |||
PEG | Di(hydroxyethyl)ether | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM | |||
UNX | Unknown atom or ion | PoSSuM |
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Download interaction data: 4GQ3
Structure summary
Code : | 4GQ3 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSCRIPTION/TRANSCRIPTION inhibitor | ||||||||||||
Title : | Human menin with bound inhibitor MI-2 | ||||||||||||
Release Data : | 2012-09-19 | ||||||||||||
Compound : |
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Source : |
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Authors : | Shi, A., Murai, M.J., He, S., Lund, G.L., Hartley, T., Purohit, T., Reddy, G., Chruszcz, M., Grembecka, J., Cierpicki, T. | ||||||||||||
Keywords : | Tumor Suppressor, Nucleus, TRANSCRIPTION-TRANSCRIPTION inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.56 Å ) | ||||||||||||
Citation : |
Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia.
Shi, A.,Murai, M.J.,He, S.
et al.
PubMed: 22936661 |
Reaction
Chain : | A |
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UniProt : | O00255 (MEN1_HUMAN) |
Reaction : | - |