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Ligands
Code Name Style Show Link
Non-standard Residues
Code Name Show
0XO 2-methyl-D-lysine
ABA Alpha-aminobutyric acid
PG9 D-phenylglycine
Glycosylation
Code Name Emphasize
Modification
Code Name Show
ALQ 2-methyl-propionic acid
Code : 4GM9   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION/TRANSCRIPTION INHIBITOR
Title : Crystal structure of human WD repeat domain 5 with compound MM-401
Release Data : 2014-02-19
Compound :
mol_id molecule chains synonym
1 WD repeat-containing protein 5 A,B WDR5, BMP2-induced 3-kb gene protein
fragment: UNP residues 22-334
mol_id molecule chains
2 MM-401 E,F
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:469008)
gene: WDR5, BIG3
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: PET28b-sumo
mol_id organism_scientific
2
synthetic: yes
Authors : Karatas, H., Townsend, E.C., Chen, Y., Bernard, D., Liu, L., Dou, Y., Lei, M., Wang, S.
Keywords : MLL1, histone methyltransferase, WD40, TRANSCRIPTION-TRANSCRIPTION INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.100 Å )
Citation :

Crystal structure of human WD repeat domain 5 with compound MM-401

Karatas, H.,Townsend, E.C.,Chen, Y.  et al.
To be Published 

Chain : A, B
UniProt : P61964 (WDR5_HUMAN)
Reaction : -