PDB ID: 4FZB
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Structure summary
Code : | 4FZB PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Structure of thymidylate synthase ThyX complexed to a new inhibitor | ||||||||||||
Release Data : | 2013-05-22 | ||||||||||||
Compound : |
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Source : |
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Authors : | Basta, T., Boum, Y., Briffotaux, J., Becker, H.F., Lamarre-Jouenne, I., Lambry, J.C., Skouloubris, S., Liebl, U., van Tilbeurgh, H., Graille, M., Myllylkallio, H. | ||||||||||||
Keywords : | Homotetramer, FAD-dependent Thymidylate synthase, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.59 Å ) | ||||||||||||
Citation : |
Mechanistic and structural basis for inhibition of thymidylate synthase ThyX.
Basta, T.,Boum, Y.,Briffotaux, J.
et al.
PubMed: 23155486 |
Reaction
Chain : | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | ||||||||
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UniProt : | O41156 (THYX_PBCV1) | ||||||||
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