PDB ID: 4FYN
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Structure summary
Code : | 4FYN PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal structure of spleen tyrosine kinase complexed with 3-(8-{4-[Ethyl-(2-hydroxy-ethyl)-amino]-phenylamino}-imidazo[1,2-a]pyrazin-5-yl)-phenol | ||||||||||||
Release Data : | 2013-01-30 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kuglstatter, A., Villasenor, A.G. | ||||||||||||
Keywords : | kinase inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.318 Å ) | ||||||||||||
Citation : |
Rational design of highly selective spleen tyrosine kinase inhibitors.
Lucas, M.C.,Goldstein, D.M.,Hermann, J.C.
et al.
PubMed: 23151054 |
Reaction
Chain : | A | ||||||||
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UniProt : | P43405 (KSYK_HUMAN) | ||||||||
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