Het-PDB Navi2 (PDB: 4FSF)

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Ligands
Code	Name		Style	Show	Link
0W0	(4r,5s,8z)-8-(2-amino-1,3-thiazol-4-yl)-1-[3-(1,5-dihydroxy-4-oxo-1,4-dihydropyridin-2-yl)-1,2-oxazol-5-yl]-5-formyl-11,11-dimethyl-1,7-dioxo-4-(sulfoamino)-10-oxa-2,6,9-triazadodec-8-en-12-oic acid				PoSSuM

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Download interaction data: 4FSF

Code :

4FSF PDBj RCSB PDB PDBe

Header :

PENICILLIN-BINDING PROTEIN/ANTIBIOTIC

Title :

Crystal structure of Pseudomonas aeruginosa PBP3 complexed with compound 14

Release Data :

2012-10-17

Compound :

mol_id	molecule	chains
1	Penicillin-binding protein 3	A
	fragment: UNP residues 50-579

Source :

mol_id	organism_scientific	expression_system
1	Pseudomonas aeruginosa (taxid:287)	Escherichia coli (taxid:562)
	gene: ftsI

Authors :

Han, S.

Keywords :

penicillin binding protein, PENICILLIN-BINDING PROTEIN-ANTIBIOTIC complex

Exp. method :

X-RAY DIFFRACTION ( 2.20 Å )

Citation :

Novel monobactams utilizing a siderophore uptake mechanism for the treatment of gram-negative infections.

Mitton-Fry, M.J.,Arcari, J.T.,Brown, M.F. et al.
(2012) Bioorg.Med.Chem.Lett. 22 : 5989 - 5994

PDB ID: 4FSF