Het-PDB Navi2 (PDB: 4FPV)

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Color scheme of protein:

Ligands
Code	Name	Link
GOL	Glycerol	PoSSuM
MG	Magnesium ion	PoSSuM
NA	Sodium ion	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 4FPV

Code :

4FPV PDBj RCSB PDB PDBe

Header :

Hydrolase/DNA

Title :

Crystal structure of D. rerio TDP2 complexed with single strand DNA product

Release Data :

2012-10-31

Compound :

mol_id	molecule	chains	synonym
1	Tyrosyl-DNA phosphodiesterase 2	A,B	Tyr-DNA phosphodiesterase 2, 5'-tyrosyl-DNA phosphodiesterase, 5'-Tyr-DNA phosphodiesterase, TRAF and TNF receptor-associated protein homolog
	ec: 3.1.4.- fragment: unp residues 113-369

mol_id	molecule	chains
2	DNA (5'-D(PTPGPCPAP*G)-3')	C

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Danio rerio (taxid:7955)	Leopard danio,zebra danio,zebra fish	Escherichia coli (taxid:562)
	gene: tdp2, ttrap, ttrapl, si:ch211-81e5.5, si:dkey-218n20.5

mol_id	organism_scientific	expression_system
2	Danio rerio (taxid:7955)	Escherichia coli (taxid:562)

Authors :

Shi, K., Kurahashi, K., Aihara, H.

Keywords :

5'-phosphotyrosyl-DNA diesterase, Hydrolase-DNA complex

Exp. method :

X-RAY DIFFRACTION ( 1.73 Å )

Citation :

Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.

Shi, K.,Kurahashi, K.,Gao, R. et al.
(2012) Nat.Struct.Mol.Biol. 19 : 1372 - 1377

PDB ID: 4FPV