Brand  (β version)

color scheme of protein:


interaction residue:

chain: Hide other chain(s)

Code Name Link
GOL Glycerol
MG Magnesium ion
NA Sodium ion
Code : 4FPV
Header : Hydrolase/DNA
Title : Crystal structure of D. rerio TDP2 complexed with single strand DNA product
Release Data : 2012-10-31
Compound :
mol_id molecule chains synonym
1 Tyrosyl-DNA phosphodiesterase 2 A,B Tyr-DNA phosphodiesterase 2, 5'-tyrosyl-DNA phosphodiesterase, 5'-Tyr-DNA phosphodiesterase, TRAF and TNF receptor-associated protein homolog
ec: 3.1.4.-
fragment: unp residues 113-369
mol_id molecule chains
2 DNA (5'-D(P*TP*GP*CP*AP*G)-3') C
Source :
mol_id organism_scientific organism_common expression_system
1 Danio rerio  (taxid:7955) Leopard danio,zebra danio,zebra fish Escherichia coli  (taxid:562)
gene: tdp2, ttrap, ttrapl, si:ch211-81e5.5, si:dkey-218n20.5
mol_id organism_scientific expression_system
2 Danio rerio  (taxid:7955) Escherichia coli  (taxid:562)
Authors : Shi, K., Kurahashi, K., Aihara, H.
Keywords : 5'-phosphotyrosyl-DNA diesterase, Hydrolase-DNA complex
Exp. method : X-RAY DIFFRACTION ( 1.73 Å )
Citation :

Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.

Shi, K.,Kurahashi, K.,Gao, R.  et al.
(2012)  Nat.Struct.Mol.Biol.  19 : 1372 - 1377

PubMed: 23104058
DOI: 10.1038/nsmb.2423

Chain : A, B
UniProt : Q5XJA0 (TYDP2_DANRE)
Reaction : -