PDB ID: 4FI7
Hetero Atom Contents
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Structure summary
Code : | 4FI7 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HORMONE/HORMONE INHIBITOR | ||||||||||||
Title : | Kinetic Stabilization of transthyretin through covalent modification of K15 by 3-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)-benzenesulfonamide | ||||||||||||
Release Data : | 2013-02-20 | ||||||||||||
Compound : |
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Source : |
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Authors : | Connelly, S., Grimster, N., Wilson, I.A., Kelly, J.W. | ||||||||||||
Keywords : | hormone, binding protein, Covalent kinetic stabilizer, HORMONE-HORMONE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.4020 Å ) | ||||||||||||
Citation : |
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate.
Grimster, N.P.,Connelly, S.,Baranczak, A.
et al.
PubMed: 23350654 |
Reaction
Chain : | A, B |
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UniProt : | P02766 (TTHY_HUMAN) |
Reaction : | - |