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Ligands
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0UK 3-[(1r,2r,3r,5r,6s,7r,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-hydroxy-2-oxoethyl)-3,12,17-tris(3-hydroxy-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-1,2,5,6,7,12,17,22-octahydrocorrin-7-yl]propanoic acid
GOL Glycerol
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Code : 4FDV   PDBj   RCSB PDB   PDBe
Header : ISOMERASE
Title : CobH from Rhodobacter capsulatus (SB1003) in complex with HBA
Release Data : 2012-10-17
Compound :
mol_id molecule chains
1 Precorrin-8X methylmutase A
ec: 5.4.1.2
Source :
mol_id organism_scientific expression_system
1 Rhodobacter capsulatus  (taxid:272942) Escherichia coli  (taxid:562)
strain: ATCC BAA-309 / NBRC 16581 / SB1003
gene: cobH, RCAP_rcc02046
expression_system_vector_type: plasmid
expression_system_plasmid: pET14b
Authors : Pickersgill, R.W., Schroeder, S., Deery, E., Warren, M.J.
Keywords : doubly wound sheet, sigmatrophic rearrangement, Hydrogenobyrinic acid, ISOMERASE
Exp. method : X-RAY DIFFRACTION ( 1.68 Å )
Citation :

An enzyme-trap approach allows isolation of intermediates in cobalamin biosynthesis.

Deery, E.,Schroeder, S.,Lawrence, A.D.  et al.
(2012)  Nat.Chem.Biol.  8 : 933 - 940

PubMed: 23042036
DOI: 10.1038/nchembio.1086

Chain : A
UniProt : D5AV08 (D5AV08_RHOCB)
Reaction : -