PDB ID: 4FDH
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Structure summary
Code : | 4FDH PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR | ||||||||||||
Title : | Structure of human aldosterone synthase, CYP11B2, in complex with fadrozole | ||||||||||||
Release Data : | 2013-01-30 | ||||||||||||
Compound : |
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Source : |
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Authors : | Strushkevich, N., Shen, L., Tempel, W., Arrowsmith, C., Edwards, A., Usanov, S.A., Park, H.-W. | ||||||||||||
Keywords : | cytochrome P450, CYP11B2, Aldosterone synthase, monooxygenase, heme protein, mineralocorticoid, inhibitor, mitochondria, membrane, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.71 Å ) | ||||||||||||
Citation : |
Structural insights into aldosterone synthase substrate specificity and targeted inhibition.
Strushkevich, N.,Gilep, A.A.,Shen, L.
et al.
PubMed: 23322723 |
Reaction
Chain : | A, B, C, D, E, F, G, H, I, J, K, L | |||||||||||||||||||||||||||||||||||||||||||
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UniProt : | P19099 (C11B2_HUMAN) | |||||||||||||||||||||||||||||||||||||||||||
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