PDB ID: 4FBX
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Structure summary
Code : | 4FBX PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||||||||||||||
Title : | Complex structure of human protein kinase CK2 catalytic subunit crystallized in the presence of a bisubstrate inhibitor | ||||||||||||||||||||||||
Release Data : | 2012-10-17 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Enkvist, E., Viht, K., Bischoff, N., Vahter, J., Saaver, S., Raidaru, G., Issinger, O.-G., Niefind, K., Uri, A. | ||||||||||||||||||||||||
Keywords : | protein kinase fold, protein phosphorylation, Bisubstrate inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.330 Å ) | ||||||||||||||||||||||||
Citation : |
A subnanomolar fluorescent probe for protein kinase CK2 interaction studies.
Enkvist, E.,Viht, K.,Bischoff, N.
et al.
PubMed: 23032938 Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.
Ermakova, I.,Boldyreff, B.,Issinger, O.G.
et al.
PubMed: 12860116 The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin.
Raaf, J.,Klopffleisch, K.,Issinger, O.G.
et al.
PubMed: 18242640 Protein kinase CK2 in health and disease: Protein kinase CK2: from structures to insights.
Niefind, K.,Raaf, J.,Issinger, O.G.
PubMed: 19387553 |
Reaction
Chain : | A | ||||||||||||||
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UniProt : | P68400 (CSK21_HUMAN) | ||||||||||||||
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