PDB ID: 4F9M
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FCM | (9as)-8-acetyl-N-[(2-ethyl-4-fluoronaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[B,D]furan-4-carboxamide | PoSSuM |
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Download interaction data: 4F9M
Structure summary
Code : | 4F9M PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSCRIPTION/TRANSCRIPTION REGULATOR | ||||||||||||||||||||||||
Title : | Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator | ||||||||||||||||||||||||
Release Data : | 2012-08-08 | ||||||||||||||||||||||||
Compound : |
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Authors : | Matsui, Y., Hanzawa, H. | ||||||||||||||||||||||||
Keywords : | three-layered alpha-helical sandwich, transcription regulation, TRANSCRIPTION-TRANSCRIPTION REGULATOR complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.90 Å ) | ||||||||||||||||||||||||
Citation : |
Synthesis and biological evaluation of novel (-)-cercosporamide derivatives as potent selective PPARg modulators
Furukawa, A.,Arita, T.,Fukuzaki, T.
et al.
PubMed: 22727448 |
Reaction
Chain : | A |
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UniProt : | P37231 (PPARG_HUMAN) |
Reaction : | - |
Chain : | C | ||||||||
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UniProt : | Q15788 (NCOA1_HUMAN) | ||||||||
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