PDB ID: 4ERE
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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0R2 | [(3r,5r,6s)-1-[(2s)-1-tert-butoxy-1-oxobutan-2-yl]-5-(3-chlorophenyl)-6-(4-chlorophenyl)-2-oxopiperidin-3-yl]acetic acid | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
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Download interaction data: 4ERE
Structure summary
Code : | 4ERE PDBj RCSB PDB PDBe | ||||||||||||
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Header : | Ligase/Ligase inhibitor | ||||||||||||
Title : | crystal structure of MDM2 (17-111) in complex with compound 23 | ||||||||||||
Release Data : | 2012-05-23 | ||||||||||||
Compound : |
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Source : |
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Authors : | Huang, X. | ||||||||||||
Keywords : | MDM2, p53, protein-protein interaction, Ligase-Ligase inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.80 Å ) | ||||||||||||
Citation : |
Structure-based design of novel inhibitors of the MDM2-p53 interaction.
Rew, Y.,Sun, D.,Gonzalez-Lopez De Turiso, F.
et al.
PubMed: 22524527 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | Q00987 (MDM2_HUMAN) | ||||||||
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