Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
A3P Adenosine-3'-5'-diphosphate
Modified Residues
Code Name Link
0UZ (2r)-amino(3-chloro-4-hydroxyphenyl)ethanoic acid
3FG (2s)-amino(3,5-dihydroxyphenyl)ethanoic acid
3MY 3-chloro-D-tyrosine
GHP (2r)-amino(4-hydroxyphenyl)ethanoic acid
OMY (betar)-3-chloro-beta-hydroxy-L-tyrosine
Code : 4EEC
Header : TRANSFERASE/TRANSFERASE INHIBITOR
Title : Crystal Structure of the glycopeptide antibiotic sulfotransferase StaL complexed with A3P and desulfo-A47934.
Release Data : 2012-07-04
Compound :
mol_id molecule chains
1 StaL A,B
mol_id molecule chains
2 desulfo-A47934 C
Source :
mol_id organism_scientific expression_system
1 Streptomyces toyocaensis  (taxid:55952) Escherichia coli  (taxid:469008)
strain: NRRL 15009
gene: stal
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET28a
mol_id organism_scientific expression_system
2 Streptomyces toyocaensis  (taxid:55952) Streptomyces toyocaensis  (taxid:55952)
Authors : Shi, R., Cygler, M.
Keywords : sulfotransferase, glycopeptide aglycone complex, Glycopeptide antibiotic sulfotransferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.7000 Å )
Citation :

Structural basis of sulfonation of the glycopeptide antibiotic scaffold by the sulfotransferase StaL

Shi, R.,Munger, C.,Kalan, L.  et al.
(2012)  Proc.Natl.Acad.Sci.USA 

Chain : A, B
UniProt : Q8KLM3 (STAL_STRTO)
Reaction : 3'-phosphoadenylyl sulfate + desulfo-A47934 = adenosine 3',5'-bisphosphate + A47934.