Brand  (β version)

PDB ID: 4EAD

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Ligands
Code Name Style Show Link
0NP 2',3'-dideoxy-2'-fluoro-3'-triaza-1,2-dien-2-ium-1-yluridine PoSSuM
GOL Glycerol PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
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Structure summary

Code : 4EAD   PDBj   RCSB PDB   PDBe
Header : Transferase/Transferase inhibitor
Title : Thymidine phosphorylase from E.coli with 3'-azido-2'-fluoro-dideoxyuridine
Release Data : 2013-03-27
Compound :
mol_id molecule chains synonym
1 Thymidine phosphorylase A TdRPase
ec: 2.4.2.4
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:83333) Escherichia coli  (taxid:469008)
strain: K12
gene: b4382, deoA, JW4345, tpp, ttg
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pER-Thy1.
Authors : Timofeev, V.I., Abramchik, Y.A., Esipov, R.S., Kuranova, I.P.
Keywords : Thymidine phosphorylase, Transferase-Transferase inhibitor complex
Exp. method : X-RAY DIFFRACTION ( 1.50 Å )
Citation :

Thymidine phosphorylase from E.coli with 3'-azido-2'-fluoro-dideoxyuridine

Timofeev, V.I.,Abramchik, Y.A.,Esipov, R.S.  et al.
To be Published 

Reaction

Chain : A
UniProt : P07650 (TYPH_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine 2.4.2.4 -
-