PDB ID: 4E4N
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Structure summary
Code : | 4E4N PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | JAK1 kinase (JH1 domain) in complex with compound 49 | ||||||||||||
Release Data : | 2012-05-30 | ||||||||||||
Compound : |
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Source : |
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Authors : | Eigenbrot, C. | ||||||||||||
Keywords : | o-phosphotyrosine, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.90 Å ) | ||||||||||||
Citation : |
Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors.
Kulagowski, J.J.,Blair, W.,Bull, R.J.
et al.
PubMed: 22591402 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P23458 (JAK1_HUMAN) | ||||||||
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