PDB ID: 4DST
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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9LI | 2-(4,6-dichloro-2-methyl-1h-indol-3-yl)ethanamine | PoSSuM | |||
ACT | Acetate ion | PoSSuM | |||
DMS | Dimethyl sulfoxide | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM | |||
GCP | Phosphomethylphosphonic acid guanylate ester | PoSSuM | |||
GOL | Glycerol | PoSSuM | |||
MG | Magnesium ion | PoSSuM |
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Download interaction data: 4DST
Structure summary
Code : | 4DST PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity | ||||||||||||
Release Data : | 2012-04-04 | ||||||||||||
Compound : |
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Source : |
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Authors : | Oh, A., Maurer, T., Garrenton, L.S., Pitts, K., Anderson, D.J., Skelton, N.J., Fauber, B.P., Pan, B., Malek, S., Stokoe, D., Ludlam, M., Bowman, K.K., Wu, J., Giannetti, A.M., Starovasnik, M.A., Mellman, I., Jackson, P.K., Ruldolph, J., Fang, G., Wang, W. | ||||||||||||
Keywords : | Small G-protein, Signaling, Hydrolase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.3 Å ) | ||||||||||||
Citation : |
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Maurer, T.,Garrenton, L.S.,Oh, A.
et al.
PubMed: 22431598 |
Reaction
Chain : | A | ||||||||
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UniProt : | P01116 (RASK_HUMAN) | ||||||||
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