PDB ID: 4DHF
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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0K6 | 7-cyclopentyl-2-({1-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-3-yl}amino)-7h-pyrrolo[2,3-D]pyrimidine-6-carboxamide | PoSSuM | |||
PO4 | Phosphate ion | PoSSuM | |||
MG | Magnesium ion | PoSSuM |
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Download interaction data: 4DHF
Structure summary
Code : | 4DHF PDBj RCSB PDB PDBe | ||||||||||||
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Header : | transferase/transferase inhibitor | ||||||||||||
Title : | Structure of Aurora A mutant bound to Biogenidec cpd 15 | ||||||||||||
Release Data : | 2012-07-18 | ||||||||||||
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Authors : | Silvian, L., Marcotte, D.J. | ||||||||||||
Keywords : | Ser/Thr kinase mitotic kinase pyrazolopyrimidine, phosphorylation, TPX2, transferase-transferase inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.80 Å ) | ||||||||||||
Citation : |
Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors.
Le Brazidec, J.Y.,Pasis, A.,Tam, B.
et al.
PubMed: 22607669 |
Reaction
Chain : | A, B | ||||||||||||
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UniProt : | O14965 (AURKA_HUMAN) | ||||||||||||
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