PDB ID: 4DFF
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Structure summary
Code : | 4DFF PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||
Title : | The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia | ||||||||||||
Release Data : | 2012-03-14 | ||||||||||||
Compound : |
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Source : |
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Authors : | Ho, G.D., Seganish, W.M., Bercovici, A., Tulshian, D., Greenlee, W.J., Van Rijn, R., Hruza, A., Xiao, L., Rindgen, D., Mullins, D., Guzzi, M., Zhang, X., Bleichardt, C., Hodgson, R. | ||||||||||||
Keywords : | Zn binding, Mg binding, HYDROLASE-HYDROLASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.11 Å ) | ||||||||||||
Citation : |
The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia.
Ho, G.D.,Michael Seganish, W.,Bercovici, A.
et al.
PubMed: 22377514 |
Reaction
Chain : | A, B | ||||||||||||||||
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UniProt : | Q9Y233 (PDE10_HUMAN) | ||||||||||||||||
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