Het-PDB Navi2 (PDB: 4DA3)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
0DX	4,9-bis{[3-(4-methylpiperazin-1-yl)propyl]amino}-2,7-bis[3-(morpholin-4-yl)propyl]benzo[lmn][3,8]phenanthroline-1,3,6,8(2h,7h)-tetrone				PoSSuM
K	Potassium ion				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 4DA3

Code :

4DA3 PDBj RCSB PDB PDBe

Header :

DNA

Title :

Crystal structure of an intramolecular human telomeric DNA G-quadruplex 21-mer bound by the naphthalene diimide compound MM41.

Release Data :

2013-01-30

Compound :

mol_id	molecule	chains
1	DNA (5'-D(GPGPGPTPTPAPGPGPGPTPTPAPGPGPGPTPTPAPGPGP*G)-3')	A

Source :

mol_id	organism_scientific
1	Synthetic DNA (taxid:32630)
	synthetic: yes other_details: DNA synthesized by standard phosphoramidite chemistry.

Authors :

Collie, G.W., Neidle, S.

Keywords :

intramolecular, ligand-complex, G-quadruplex, telomere, DNA

Exp. method :

X-RAY DIFFRACTION ( 2.40 Å )

Citation :

Structure-based design and evaluation of naphthalene diimide g-quadruplex ligands as telomere targeting agents in pancreatic cancer cells.

Micco, M.,Collie, G.W.,Dale, A.G. et al.
(2013) J.Med.Chem. 56 : 2959 - 2974

PDB ID: 4DA3