PDB ID: 4CQ8
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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FMN | Flavin mononucleotide | PoSSuM | |||
ORO | Orotic acid | PoSSuM | |||
JBW | 5-(4-cyano-2-methyl-1h-benzimidazol-1-yl)-N-cyclopropylthiophene-2-carboxamide | PoSSuM |
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Download interaction data: 4CQ8
Structure summary
Code : | 4CQ8 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) in complex with Genz-669178 | ||||||||||||
Release Data : | 2014-04-30 | ||||||||||||
Compound : |
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Authors : | Rowland, P. | ||||||||||||
Keywords : | OXIDOREDUCTASE, DHODH | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.98 Å ) | ||||||||||||
Citation : |
In Vitro Resistance Selections for Plasmodium Falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-Binding Site and Altered Growth.
Ross, L.S.,Javier Gamo, F.,Lafuente-Monasterio, M.J.E.
et al.
PubMed: 24782313 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | Q54A96 (Q54A96_PLAFA) | ||||||||
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