Het-PDB Navi2 (PDB: 4CB5)

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Ligands
Code	Name		Style	Show	Link
93G	9-N-(3-carboxy-4-hydroxyphenyl)ketomethyl-7-N-methylguanine				PoSSuM
CL	Chloride ion				PoSSuM

Non-standard Residues
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Download interaction data: 4CB5

Code :

4CB5 PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 8f)

Release Data :

2013-10-30

Compound :

mol_id	molecule	chains	synonym
1	POLYMERASE BASIC SUBUNIT 2	A	H5N1 INFLUENZA POLYMERASE PB2 SUBUNIT
	fragment: CAP-BINDING DOMAIN, RESIDUES 318-483

Source :

mol_id	organism_scientific	expression_system
1	Influenza A virus (A/duck/Shantou/4610/2003(H5N1)) (taxid:365107)	Escherichia coli BL21 (taxid:511693)
	expression_system_variant: CODONPLUS RIL expression_system_vector_type: PLASMID expression_system_plasmid: PET-M11

Authors :

Pautus, S., Sehr, P., Lewis, J., Fortune, A., Wolkerstorfer, A., Szolar, O., Gulligay, D., Lunardi, T., Decout, J.L., Cusack, S.

Keywords :

TRANSFERASE, CAP-BINDING INHIBITORS

Exp. method :

X-RAY DIFFRACTION ( 1.50 Å )

Citation :

New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain

Pautus, S.,Sehr, P.,Lewis, J. et al.
(2013) J.Med.Chem. 56 : 8915

PDB ID: 4CB5