PDB ID: 4BU3
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Structure summary
Code : | 4BU3 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of human tankyrase 2 in complex with 2-phenyl-3,4- dihydroquinazolin-4-one | ||||||||||||
Release Data : | 2013-10-30 | ||||||||||||
Compound : |
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Source : |
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Authors : | Haikarainen, T., Narwal, M., Lehtio, L. | ||||||||||||
Keywords : | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.15 Å ) | ||||||||||||
Citation : |
Para-Substituted 2-Phenyl-3,4-Dihydroquinazolin-4-Ones as Potent and Selective Tankyrase Inhibitors.
Haikarainen, T.,Koivunen, J.,Narwal, M.
et al.
PubMed: 24130191 |
Reaction
Chain : | A, B | ||||||||||||||||
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UniProt : | Q9H2K2 (TNKS2_HUMAN) | ||||||||||||||||
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