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Ligands
Code Name Style Show Link
HEM Protoporphyrin ix containing Fe
JZ3 Guaiacol
Non-standard Residues
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Glycosylation
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Code : 4A78   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : cytochrome C peroxidase M119W in complex with guiacol
Release Data : 2012-11-07
Compound :
mol_id molecule chains synonym
1 CYTOCHROME C PEROXIDASE, MITOCHONDRIAL A CCP
ec: 1.11.1.5
mutation: YES
Source :
mol_id organism_scientific organism_common expression_system
1 SACCHAROMYCES CEREVISIAE  (taxid:4932) BAKER'S YEAST ESCHERICHIA COLI  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: PT7CCP/Y39A/N184R/M119W
Authors : Murphy, E.J., Metcalfe, C.L., Raven, E.L., Moody, P.C.E.
Keywords : OXIDOREDUCTASE, TRANSIT PEPTIDE, HYDROGEN PEROXIDE, IRON, HEME, ISONIAZID, MITOCHONDRION, METAL-BINDING
Exp. method : X-RAY DIFFRACTION ( 2.01 Å )
Citation :

Crystal Structure of Guaiacol and Phenol Bound to a Heme Peroxidase.

Murphy, E.J.,Metcalfe, C.L.,Nnamchi, C.  et al.
(2012)  FEBS J.  279 : 1632

PubMed: 22093282
DOI: 10.1111/J.1742-4658.2011.08425.X

Chain : A
UniProt : P00431 (CCPR_YEAST)
Reaction: EC: Evidence:
Physiological Direction:
2 Fe(II)-[cytochrome c] + 2 H(+) + H2O2 = 2 Fe(III)- [cytochrome c] + 2 H2O 1.11.1.5 -
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