Het-PDB Navi2 (PDB: 4A1O)

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Ligands
Code	Name	Link
AMZ	Aminoimidazole 4-carboxamide ribonucleotide	PoSSuM
JLN	5-(formylamino)-1-(5-O-phosphono-beta-D-ribofuranosyl)-1h-imidazole-4-carboxylic acid	PoSSuM
K	Potassium ion	PoSSuM
PO4	Phosphate ion	PoSSuM

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Download interaction data: 4A1O

Code :

4A1O PDBj RCSB PDB PDBe

Header :

TRANSFERASE-HYDROLASE

Title :

Crystal structure of Mycobacterium tuberculosis PurH complexed with AICAR and a novel nucleotide CFAIR, at 2.48 A resolution.

Release Data :

2011-09-28

Compound :

mol_id	molecule	chains	synonym
1	BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH	A,B	PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE, AICAR TRANSFORMYLASE, IMP CYCLOHYDROLASE, ATIC, IMP SYNTHASE, INOSINICASE
	ec: 2.1.2.3, 3.5.4.10

Source :

mol_id	organism_scientific	expression_system
1	MYCOBACTERIUM TUBERCULOSIS (taxid:83332)	ESCHERICHIA COLI (taxid:469008)
	strain: H37RV atcc: 25618 expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: PDEST17

Authors :

Le Nours, J., Bulloch, E.M.M., Zhang, Z., Greenwood, D.R., Middleditch, M.J., Dickson, J.M.J., Baker, E.N.

Keywords :

TRANSFERASE-HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 2.48 Å )

Citation :

Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium Tuberculosis Reveal a Novel Bound Nucleotide.

Le Nours, J.,Bulloch, E.M.M.,Zhang, Z. et al.
(2011) J.Biol.Chem. 286 : 40706

PDB ID: 4A1O