Het-PDB Navi2 (PDB: 4A03)

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Ligands
Code	Name	Link
F98	3-[ethanoyl(hydroxy)amino]propylphosphonic acid	PoSSuM
GOL	Glycerol	PoSSuM
MN	Manganese (II) ion	PoSSuM
NDP	Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate	PoSSuM

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Download interaction data: 4A03

Code :

4A03 PDBj RCSB PDB PDBe

Header :

OXIDOREDUCTASE

Title :

Crystal Structure of Mycobacterium tuberculosis DXR in complex with the antibiotic FR900098 and cofactor NADPH

Release Data :

2012-01-18

Compound :

mol_id	molecule	chains	synonym
1	1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE	A,B	DXP REDUCTOISOMERASE, 1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERASE, 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE SYNTHASE
	ec: 1.1.1.267 fragment: RESIDUES 2-389

Source :

mol_id	organism_scientific	expression_system
1	MYCOBACTERIUM TUBERCULOSIS (taxid:83332)	ESCHERICHIA COLI (taxid:511693)
	strain: H37RV expression_system_strain: BL21 expression_system_variant: AI expression_system_vector_type: PLASMID expression_system_plasmid: PEXP5CT/TOPO

Authors :

Bjorkelid, C., Bergfors, T., Jones, T.A.

Keywords :

OXIDOREDUCTASE, FR900098, MEP PATHWAY

Exp. method :

X-RAY DIFFRACTION ( 1.65 Å )

Citation :

Structural Studies on Mycobacterium Tuberculosis Dxr in Complex with the Antibiotic Fr-900098.

Bjorkelid, C.,Bergfors, T.,Unge, T. et al.
(2012) Acta Crystallogr.,Sect.D 68 : 134

PDB ID: 4A03