PDB ID: 4ZQC
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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DMS | Dimethyl sulfoxide | PoSSuM | |||
F6F | 2-{[4-(trifluoromethoxy)benzoyl]amino}ethyl dihydrogen phosphate | PoSSuM | |||
NA | Sodium ion | PoSSuM | |||
PLP | Pyridoxal-5'-phosphate | PoSSuM |
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Download interaction data: 4ZQC
Structure summary
Code : | 4ZQC PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | LYASE/LYASE INHIBITOR | ||||||||||||||||||||||||
Title : | Tryptophan Synthase from Salmonella typhimurium in complex with two molecules of N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor in the alpha-site and a single F6F molecule in the beta-site at 1.54 Angstrom resolution. | ||||||||||||||||||||||||
Release Data : | 2016-02-10 | ||||||||||||||||||||||||
Compound : |
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Authors : | Hilario, E., Caulkins, B.G., Young, R.P., Dunn, M.F., Mueller, L.J., Fan, L. | ||||||||||||||||||||||||
Keywords : | lyase, tryptophan biosynthesis, Salmonella typhimurium, F6F, inhibitor, allosteric enzyme, aromatic amino acid biosynthesis, pyridoxal phosphate, lyase-lyase inhibitor complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.5400 Å ) | ||||||||||||||||||||||||
Citation : |
Visualizing the tunnel in tryptophan synthase with crystallography: Insights into a selective filter for accommodating indole and rejecting water.
Hilario, E.,Caulkins, B.G.,Huang, Y.M.
et al.
PubMed: 26708480 |
Reaction
Chain : | A | ||||||||
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UniProt : | P00929 (TRPA_SALTY) | ||||||||
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Chain : | B | ||||||||
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UniProt : | P0A2K1 (TRPB_SALTY) | ||||||||
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