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Ligands
Code Name Style Show Link
CDC [2-cytidylate-O'-phosphonyloxyl]-ethyl-trimethyl-ammonium
P33 3,6,9,12,15,18-hexaoxaicosane-1,20-diol
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Code : 4ZCS   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with CDP-choline
Release Data : 2016-08-17
Compound :
mol_id molecule chains
1 Choline-phosphate cytidylyltransferase A,C,E,B,D,F
ec: 2.7.7.15
fragment: UNP residues 581-775
Source :
mol_id organism_scientific expression_system
1 Plasmodium falciparum (isolate 3D7)  (taxid:36329) Escherichia coli  (taxid:562)
gene: PF3D7_1316600
Authors : Guca, E., Hoh, F., Guichou, J.-F., Cerdan, R.
Keywords : enzyme, malaria, cytidylyltransferase, phosphatidylcholine, transferase
Exp. method : X-RAY DIFFRACTION ( 2.45 Å )
Citation :

Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis.

Guca, E.,Nagy, G.N.,Hajdu, F.  et al.
(2018)  Sci Rep  8 : 11215 - 11215

PubMed: 30046154
DOI: 10.1038/s41598-018-29500-9

Chain : A, C, E, B, D, F
UniProt : Q8IEE9 (Q8IEE9_PLAF7)
Reaction : -