Brand  (β version)

PDB ID: 4YCL

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Ligands
Code Name Style Show Link
CZA (6ar,11as,11br)-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo[1',2':2,3]isoindolo[4,5,6-Cd]indol-11-one PoSSuM
K Potassium ion PoSSuM
MG Magnesium ion PoSSuM
Non-standard Residues
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Glycosylation
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ACE Acetyl group

Structure summary

Code : 4YCL   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of the SR CA2+-ATPASE with bound CPA
Release Data : 2015-04-01
Compound :
mol_id molecule chains synonym
1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 A SR Ca(2+)-ATPase 1,Calcium pump 1,Calcium-transporting ATPase sarcoplasmic reticulum type,fast twitch skeletal muscle isoform,Endoplasmic reticulum class 1/2 Ca(2+) ATPase
ec: 3.6.3.8
Source :
mol_id organism_scientific organism_common
1 Oryctolagus cuniculus  (taxid:9986) Rabbit
Authors : Ogawa, H., Takahashi, M., Kondou, Y., Toyoshima, C.
Keywords : MEMBRANE PROTEIN, P-TYPE ATPASE, HAD FOLD, ion pump, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 3.250 Å )
Citation :

Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors

Takahashi, M.,Kondou, Y.,Toyoshima, C.
(2007)  Proc.Natl.Acad.Sci.Usa  104 : 5800 - 5805

PubMed: 17389383
DOI: 10.1073/pnas.0700979104

Reaction

Chain : A
UniProt : P04191 (AT2A1_RABIT)
Reaction: EC: Evidence:
Physiological Direction:
ATP + Ca(2+)(in) + H2O = ADP + Ca(2+)(out) + H(+) + phosphate 7.2.2.10 PubMed:10914677, PubMed:11438520, PubMed:15189864, PubMed:18075584, PubMed:23996003, PubMed:29081402, PubMed:8117720
left-to-right PubMed:10914677