PDB ID: 4Y14
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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CL | Chloride ion | PoSSuM | |||
TRS | 2-amino-2-hydroxymethyl-propane-1,3-diol | PoSSuM | |||
GOL | Glycerol | PoSSuM | |||
C0A | 3-bromo-4-[difluoro(phosphono)methyl]-N-methyl-nalpha-(methylsulfonyl)-L-phenylalaninamide | PoSSuM |
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Download interaction data: 4Y14
Structure summary
Code : | 4Y14 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE/INHIBITOR | ||||||||||||
Title : | Structure of protein tyrosine phosphatase 1B complexed with inhibitor (PTP1B:CPT157633) | ||||||||||||
Release Data : | 2015-08-05 | ||||||||||||
Compound : |
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Authors : | Choy, M.S., Connors, C., Page, R., Peti, W. | ||||||||||||
Keywords : | Tyrosine inhibitor complex, HYDROLASE, PROTEIN BINDING, HYDROLASE-INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.8980 Å ) | ||||||||||||
Citation : |
PTP1B inhibition suggests a therapeutic strategy for Rett syndrome.
Krishnan, N.,Krishnan, K.,Connors, C.R.
et al.
PubMed: 26214522 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P18031 (PTN1_HUMAN) | ||||||||
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