Het-PDB Navi2 (PDB: 4XXR)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
K	Potassium ion	PoSSuM
JSD	[(1,2,3,4,5-eta)-1-(4-{[(4-carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl)methyl]amino}-4-oxobutanoyl)cyclopentadienyl][(1,2,3,4,5-eta)-cyclopentadienyl]ruthenium	PoSSuM
JSC	[(1,2,3,4,5-eta)-1-(4-{[carboxy(4-carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl)methyl]amino}-4-oxobutanoyl)cyclopentadienyl][(1,2,3,4,5-eta)-cyclopentadienyl]ruthenium	PoSSuM
JSE	[(1,2,3,4,5-eta)-1-(4-{[carboxy(4-carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl)methyl]amino}-4-oxobutanoyl)cyclopentadienyl][(1,2,3,4,5-eta)-cyclopentadienyl]ruthenium	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 4XXR

Code :

4XXR PDBj RCSB PDB PDBe

Header :

HYDROLASE/ANTIBIOTIC

Title :

Atomic Resolution X-Ray Crystal Structure of a Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with CTX-M-14 E166A Beta-Lactamase

Release Data :

2015-03-18

Compound :

mol_id	molecule	chains
1	CTX-M-14 Class A Beta-Lactamase	A,B
	ec: 3.5.2.6 fragment: UNP residues 29-291 mutation: E166A

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (taxid:562)	Escherichia coli (taxid:562)
	gene: blaCTX-M-14, beta-lactamase CTX-M-14, bla-CTX-M-14a, blaCTX-M-14a, blaCTX-M-14b, blaCTX-M-14c, blaCTX-M-27b, blatoho-3, blaUOE-2, CTX-M-14, ETN48_p0088, pCT_085, pHK01_011

Authors :

Lewandowski, E.M., Chen, Y.

Keywords :

Beta-Lactamase Organometallic Ruthenocene CTX-M-14, HYDROLASE-ANTIBIOTIC complex

Exp. method :

X-RAY DIFFRACTION ( 1.18 Å )

Citation :

Antibacterial properties and atomic resolution X-ray complex crystal structure of a ruthenocene conjugated beta-lactam antibiotic.

Lewandowski, E.M.,Skiba, J.,Torelli, N.J. et al.
(2015) Chem.Commun.(Camb.) 51 : 6186 - 6189

PDB ID: 4XXR