Brand  (β version)

PDB ID: 4XPD

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
ACO Acetyl coenzyme *a PoSSuM
CMC Carboxymethyl coenzyme *a PoSSuM
G4P Guanosine-5',3'-tetraphosphate PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 4XPD   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of yeast N-terminal acetyltransferase NatE (ppGpp) in complex with a bisubstrate
Release Data : 2016-07-20
Compound :
mol_id molecule chains synonym
1 N-terminal acetyltransferase A complex subunit NAT1 A NatA complex subunit NAT1,Amino-terminal,alpha-amino,acetyltransferase 1
mol_id molecule chains synonym
2 N-terminal acetyltransferase A complex catalytic subunit ARD1 B NatA complex subunit ARD1,Arrest-defective protein 1
ec: 2.3.1.88
mol_id molecule chains synonym
3 N-terminal acetyltransferase A complex subunit NAT5 C NatA complex subunit NAT5
ec: 2.3.1.-
mol_id molecule chains
4 human ACTH8 F
Source :
mol_id organism_scientific organism_common expression_system
1 Saccharomyces cerevisiae  (taxid:4932) Baker's yeast Escherichia coli  (taxid:562)
mol_id organism_scientific organism_common expression_system
2 Saccharomyces cerevisiae  (taxid:4932) Baker's yeast Escherichia coli  (taxid:562)
mol_id organism_scientific organism_common expression_system
3 Saccharomyces cerevisiae  (taxid:4932) Baker's yeast Escherichia coli  (taxid:562)
mol_id organism_scientific organism_common
4 Homo sapiens  (taxid:9606) Human
synthetic: yes
Authors : Dong, J., Wang, S., York, J.D.
Keywords : N-terminal acetyltransferase, NatE, ppGpp, bisubstrate, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.81 Å )
Citation :

Crystal structure of yeast N-terminal acetyltransferase NatE (ppGpp) in complex with a bisubstrate

Dong, J.,Wang, S.,York, J.D.
To Be Published 

Reaction

Chain : A
UniProt : P12945 (NAT1_YEAST)
Reaction : -
Chain : B
UniProt : P07347 (ARD1_YEAST)
Reaction: EC: Evidence:
Physiological Direction:
N-terminal glycyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetylglycyl-[protein] + CoA + H(+) 2.3.1.255 PubMed:1600941, PubMed:2551674
-
N-terminal L-alanyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-alanyl-[protein] + CoA + H(+) 2.3.1.255 PubMed:1600941, PubMed:2551674
-
N-terminal L-seryl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[protein] + CoA + H(+) 2.3.1.255 PubMed:1600941, PubMed:2551674
-
N-terminal L-valyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-valyl-[protein] + CoA + H(+) 2.3.1.255 PubMed:1600941, PubMed:2551674
-
N-terminal L-cysteinyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-cysteinyl-[protein] + CoA + H(+) 2.3.1.255 PubMed:1600941, PubMed:2551674
-
N-terminal L-threonyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-threonyl-[protein] + CoA + H(+) 2.3.1.255 PubMed:1600941, PubMed:2551674
-
Chain : C
UniProt : Q08689 (NAT5_YEAST)
Reaction: EC: Evidence:
Physiological Direction:
N-terminal L-methionyl-L-alanyl-[protein] + acetyl-CoA = N- terminal N(alpha)-acetyl-L-methionyl-L-alanyl-[protein] + CoA + H(+) 2.3.1.258 PubMed:25886145
-
N-terminal L-methionyl-L-seryl-[protein] + acetyl-CoA = N- terminal N(alpha)-acetyl-L-methionyl-L-seryl-[protein] + CoA + H(+) 2.3.1.258 PubMed:25886145
-
N-terminal L-methionyl-L-valyl-[protein] + acetyl-CoA = N- terminal N(alpha)-acetyl-L-methionyl-L-valyl-[protein] + CoA + H(+) 2.3.1.258 PubMed:25886145
-
N-terminal L-methionyl-L-threonyl-[protein] + acetyl-CoA = N- terminal N(alpha)-acetyl-L-methionyl-L-threonyl-[protein] + CoA + H(+) 2.3.1.258 PubMed:25886145
-
N-terminal L-methionyl-L-lysyl-[protein] + acetyl-CoA = N- terminal N(alpha)-acetyl-L-methionyl-L-lysyl-[protein] + CoA + H(+) 2.3.1.258 PubMed:25886145
-
N-terminal L-methionyl-L-leucyl-[protein] + acetyl-CoA = N- terminal N(alpha)-acetyl-L-methionyl-L-leucyl-[protein] + CoA + H(+) 2.3.1.258 PubMed:25886145
-
N-terminal L-methionyl-L-phenylalanyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-phenylalanyl-[protein] + CoA + H(+) 2.3.1.258 PubMed:25886145
-
N-terminal L-methionyl-L-tyrosyl-[protein] + acetyl-CoA = N- terminal N(alpha)-acetyl-L-methionyl-L-tyrosyl-[protein] + CoA + H(+) 2.3.1.258 PubMed:25886145
-