Het-PDB Navi2 (PDB: 4XIC)

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Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
NI	Nickel (II) ion				PoSSuM
MPD	(4s)-2-methyl-2,4-pentanediol				PoSSuM

Non-standard Residues
Code	Name	Show
C2S	Cytidine-5'-dithiophosphorate

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 4XIC

Code :

4XIC PDBj RCSB PDB PDBe

Header :

Transcription Regulator/DNA

Title :

ANTPHD WITH 15BP di-thioate modified DNA DUPLEX

Release Data :

2015-11-25

Compound :

mol_id	molecule	chains
1	Homeotic protein antennapedia	A,D
	fragment: UNP residues 297-356

mol_id	molecule	chains
2	DNA (5'-D(APGPAPAPAPGPCP(C2S)PAPTPTPAPGPAP*G)-3')	B,E

mol_id	molecule	chains
3	DNA (5'-D(TPCPTPCPTPAPAPTPGPGPCPTPTPTP*C)-3')	C,F

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Drosophila melanogaster (taxid:7227)	Fruit fly	Escherichia coli (taxid:562)
	gene: Antp, CG1028

mol_id	organism_scientific
2	Unidentified (taxid:32644)
	synthetic: yes

mol_id	organism_scientific
3	Unidentified (taxid:32644)
	synthetic: yes

Authors :

White, M.A., Zandarashvili, L., Iwahara, J.

Keywords :

DNA Binding, Methylated DNA, ZINC FINGER, TRANSCRIPTION, Transcription Regulator-DNA complex

Exp. method :

X-RAY DIFFRACTION ( 2.690 Å )

Citation :

Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.

Zandarashvili, L.,Nguyen, D.,Anderson, K.M. et al.
(2015) Biophys.J. 109 : 1026 - 1037

Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.

Hashimoto, H.,Olanrewaju, Y.O.,Zheng, Y. et al.
(2014) Genes Dev. 28 : 2304 - 2313

PDB ID: 4XIC