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Ligands
Code Name Style Show Link
CKI N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide
SO4 Sulfate ion
Non-standard Residues
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Glycosylation
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Code : 4XHL   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE/TRANSFERASE INHIBITOR
Title : Structure of S. cerevisiae Hrr25 1-394 (K38R mutant)
Release Data : 2016-01-06
Compound :
mol_id molecule chains
1 Casein kinase I homolog HRR25 A
ec: 2.7.11.1
fragment: UNP residues 1-394
mutation: K38R
Source :
mol_id organism_scientific organism_common expression_system
1 Saccharomyces cerevisiae  (taxid:4932) Baker's yeast Escherichia coli  (taxid:562)
gene: HRR25
Authors : Ye, Q., Corbett, K.D.
Keywords : casein kinase, monopolin, TRANSFERASE-TRANSFERASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 3.01 Å )
Citation :

Structure of the Saccharomyces cerevisiae Hrr25:Mam1 monopolin subcomplex reveals a novel kinase regulator.

Ye, Q.,Ur, S.N.,Su, T.Y.  et al.
(2016)  Embo J.  35 : 2139 - 2151

PubMed: 27491543
DOI: 10.15252/embj.201694082

Chain : A
UniProt : P29295 (HRR25_YEAST)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein] 2.7.11.1 PubMed:1495994
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ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 2.7.11.1 PubMed:1495994
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