Het-PDB Navi2 (PDB: 4V04)

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Ligands
Code	Name	Link
EDO	1,2-ethanediol	PoSSuM
0LI	3-(imidazo[1,2-B]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide	PoSSuM
SO4	Sulfate ion	PoSSuM

Non-standard Residues
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Download interaction data: 4V04

Code :

4V04 PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

FGFR1 in complex with ponatinib.

Release Data :

2014-12-10

Compound :

mol_id	molecule	chains	synonym
1	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B	A,B	FGFR1
	fragment: KINASE, UNP RESIDUES 22-359 mutation: YES

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:562)

Authors :

Tucker, J., Klein, T., Breed, J., Breeze, A., Overman, R., Phillips, C., Norman, R.A.

Keywords :

TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 2.12 Å )

Citation :

Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4

Tucker, J.A.,Klein, T.,Breed, J. et al.
(2014) Structure 22 : 1764

PDB ID: 4V04