PDB ID: 4UVX
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Structure summary
Code : | 4UVX PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-fluoro-1,2-dihydroisoquinolin-1-one | ||||||||||||
Release Data : | 2015-07-29 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Haikarainen, T., Narwal, M., Lehtio, L. | ||||||||||||
Keywords : | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.95 Å ) | ||||||||||||
Citation : |
Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro.
Paine, H.A.,Nathubhai, A.,Woon, E.C.Y.
et al.
PubMed: 26189030 |
Reaction
Chain : | A, B | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProt : | Q9H2K2 (TNKS2_HUMAN) | ||||||||||||||||
|