Het-PDB Navi2 (PDB: 4UP5)

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Ligands
Code	Name		Style	Show	Link
94W	6-methoxy-1,3-benzothiazol-2-amine				PoSSuM
ZN	Zinc ion				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 4UP5

Code :

4UP5 PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment

Release Data :

2014-11-05

Compound :

mol_id	molecule	chains	synonym
1	PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN	A	PYGO2, B9L, B-CELL LYMPHOMA 9-LIKE PROTEIN, BCL9-LIKE PROTEIN, PROTEIN BCL9-2
	fragment: PHD FINGER, HD1,RESIDUES 327-387,240-268

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_variant: CODONPLUS RIL expression_system_vector_type: PLASMID expression_system_plasmid: PETM11

Authors :

Miller, T.C.R., Fiedler, M., Rutherford, T.J., Birchall, K., Chugh, J., Bienz, M.

Keywords :

TRANSCRIPTION, PYGO, WNT SIGNALLING, HISTONE H3, FRAGMENT SCREENING

Exp. method :

X-RAY DIFFRACTION ( 1.65 Å )

Citation :

Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.

Miller, T.C.R.,Rutherford, T.J.,Birchall, K. et al.
(2014) Acs Chem.Biol. 9 : 2864

PDB ID: 4UP5