Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
MN Manganese (II) ion
0V5 (2r)-2-(phosphonooxy)propanoic acid
PO4 Phosphate ion
Code : 4UMB
Header : TRANSFERASE
Title : Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water
Release Data : 2014-10-08
Compound :
mol_id molecule chains synonym
1 PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE A,B,C,D 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE, DAHP SYNTHASE, PHOSPHO-2-KETO-3-DEOXYHEPTONATE ALDOLASE
ec: 2.5.1.54
Source :
mol_id organism_scientific expression_system
1 NEISSERIA MENINGITIDIS  (taxid:122586) ESCHERICHIA COLI  (taxid:469008)
strain: MC58
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: PT7/7
Authors : Heyes, L.C., Reichau, S., Cross, P.J., Parker, E.J.
Keywords : TRANSFERASE, DAH7PS, DAHPS, AROMATIC AMINO ACIDS, SHIKIMATE PATHWAY, OXOCARBENIUM ION, MENINGITIS
Exp. method : X-RAY DIFFRACTION ( 2.17 Å )
Citation :

Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water.

Heyes, L.C.,Reichau, S.,Cross, P.J.  et al.
(2014)  Bioorg.Chem.  57 : 242

PubMed: 25245459
DOI: 10.1016/J.BIOORG.2014.08.003

Chain : A, B, C, D
UniProt : Q9K169 (No found in current UniProtKB/SwissProt)
Reaction : -