PDB ID: 4UIY
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
5V2 | N-[1,1-bis(oxidanylidene)thian-4-yl]-5-methyl-4-oxidanylidene-7-[3-(trifluoromethyl)phenyl]thieno[3,2-C]pyridine-2-carboximidamide | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM |
Code | Name | Show |
---|
Code | Name | Emphasize |
---|
Code | Name | Show |
---|
Download interaction data: 4UIY
Structure summary
Code : | 4UIY PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | TRANSCRIPTION | ||||||||||||
Title : | N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-C- pyridine-2-carboximidamide | ||||||||||||
Release Data : | 2015-04-22 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Chung, C., Theodoulou, N.T., Bamborough, P., Humphreys, P.G. | ||||||||||||
Keywords : | TRANSCRIPTION, INHIBITOR, HISTONE, EPIGENETIC READER, BROMODOMAIN, BRD4, BROMODOMAIN CONTAINING PROTEIN 4, ANTAGONIST | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.30 Å ) | ||||||||||||
Citation : |
The Discovery of I-Brd9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
Theodoulou, N.H.,Bamborough, P.,Bannister, A.J.
et al.
PubMed: 25856009 |
Reaction
Chain : | A |
---|---|
UniProt : | O60885 (BRD4_HUMAN) |
Reaction : | - |